OS Compatibility Checker

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macOS 10.14 Mojave
Yes
macOS 10.13 High Sierra
Yes
macOS 10.12 Sierra
Yes
Mac 10.11
Yes
Mac 10.10
Yes
Mac 10.9
No

OS X Mavericks is untested and not officially supported, though may work.

Mac 10.8
No
Windows 10
Yes
Windows 8.1
Yes
Windows 8
No

The Scarlett range is unsupported on Windows 8, though may work. The range is fully tested and supported on Windows 8.1. 

Windows 7 - 64bit
Yes
Windows 7
Yes
Windows Vista64
No
Windows Vista
No
Windows XP64
No
Windows XP
No